Table 2.

Performance Characteristics of the Bio-Rad Combo Avidity Assay

	Bio-Rad combo avidity		Bio-Rad combo avidity+HIV VL >400 copies/ml
Avidity indexCohort (%)	MDRI (95% CI)HIVNET 001 N = 816	FRR% (95% CI)ALIVE+MACS+JHHCC+ES N = 1324	MDRI (95% CI)HIVNET 001 N = 804	FRR% (95% CI)ALIVE+JHHCC+MACS+ES N = 1149
20	50.6 (37.2–71.6)	0.2 (0.0–0.6)	36.8 (24.9–54.9)	0.0 (0.0–0.3)
30	84.2 (67.3–104.1)	0.7 (0.3–1.3)	63.8 (46.9–82.3)	0.4 (0.1–0.9)
40	109.6 (93.5–125.1)	1.4 (0.9–2.2)	94.4 (78.5–110.7)	0.8 (0.4–1.5)
50	135.4 (120.0–150.7)	2.1 (1.4–3.0)	108.9 (91.5–124.9)	1.1 (0.6–1.9)
60	150 (133.2–167.2)	2.9 (2.1–4.0)	118.8 (102.2–133.9)	1.7 (1.1–2.7)
70	181.5 (164.7–200.2)	4.5 (3.5–5.8)	137.5 (123.5–152.9)	2.6 (1.8–3.7)
80	205.5 (187.9–223.3)	5.3 (4.2–6.7)	152.2 (137.7–168.3)	2.9 (2.0–4.0)
90	275.6 (254.2–297.4)	8.5 (7.1–10.2)	196.7 (180.9–213.5)	4.4 (3.2–5.7)

Cohort descriptions are provided in the Methods section.

CI, confidence intervals; ES, elite suppressor; FRR, false-recent rate; MDRI, mean duration of recent infection.