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. 2016 Aug 1;32(8):791–800. doi: 10.1089/aid.2015.0313

FIG. 3.

FIG. 3.

(A) The top row shows the percentage of all CD4+ T cells (left) or all CD8+ T cells (right) in blood or CSF that were positive for CCR5. Second row: the graph shows the percentages of HIV-specific CD8+ T cells (i.e., binding MHC class I multimers) that were positive for CCR5 in blood or CSF. HC, HIV controllers (blue shapes); NC, noncontrollers (red shapes); Tx, subjects on ART with VL <50 (green shapes); Neg, HIV-negative controls (black shapes). Lines and asterisks above the graphs indicate p values for statistically significant differences between groups (*p < .05; **p < .01; ***p < 0.001). (B) Shows the percentage of all CD4+ T cells (left) or all CD8+ T cells (right) in blood or CSF that coexpressed the activation markers HLA-DR and CD38. The third panel shows the percentages of HIV-specific CD8+ T cells (i.e., binding MHC class I multimers) that were positive for both HLA-DR and CD38 in blood or CSF. Lines and asterisks above the graphs indicate p values for statistically significant differences between groups (*p < .05).