Table 2.
Least Square Means from Longitudinal Model, Their Standard Errors by Trial Arm Adjusted for Age, Being on HAART at Intake, Socioeconomic Score, Home Score, Recruitment Location, KABC Learning and Delayed Recall Scores at Baseline, and Outcome Score at Baseline
| Neuropsychology outcomes | CCRT LS mean (SE) | Limited CCRT LS mean (SE) | Control LS mean (SE) | p-Value for comparison by arm | p-Value for CCRT vs. control | p-Value for limited CCRT vs. control |
|---|---|---|---|---|---|---|
| KABC-II sequential processinga | 73.00 (0.97) | 73.26 (0.99) | 72.77 (0.91) | .93 | .86 | .71 |
| KABC-II simultaneous processing | 69.18 (1.15) | 67.35 (1.19) | 66.20 (1.09) | .14 | .05 | .47 |
| KABC-II learning* | 72.23 (1.02) | 72.43 (1.05) | 69.66 (0.96) | .08 | .06 | .05 |
| KABC-II knowledge* | 70.32 (0.97) | 67.39 (1.00) | 67.72 (0.91) | .05 | .04 | .80 |
| KABC-II planning | 62.73 (0.74) | 62.50 (0.81) | 60.45 (0.77) | .07 | .03 | .07 |
| KABC-II delayed recall | 71.93 (0.94) | 71.02 (0.97) | 69.60 (0.89) | .17 | .06 | .27 |
| KABC-II nonverbal index | 63.67 (0.98) | 63.04 (1.01) | 61.26 (0.92) | .15 | .06 | .19 |
| KABC-II mental processing index** | 63.32 (0.60) | 62.65 (0.62) | 61.13 (0.57) | .02 | <.01 | .07 |
| TOVA% omission errors | 22.35 (2.05) | 23.18 (2.12) | 21.18 (1.94) | .77 | .67 | .48 |
| TOVA% commission errors | 10.93 (1.24) | 11.63 (1.28) | 9.67 (1.17) | .50 | .44 | .25 |
| TOVA response time (msec) | 651.19 (12.53) | 659.61 (12.92) | 654.32 (11.87) | .89 | .85 | .76 |
| TOVA response time variability (msec) | 249.06 (7.85) | 249.33 (8.09) | 246.62 (7.43) | .96 | .81 | .80 |
| TOVA D prime signal detection score | 2.33 (0.12) | 2.33 (0.13) | 2.49 (0.12) | .55 | .34 | .36 |
| TOVA ADHD index | −5.57 (0.40) | −6.09 (0.42) | −5.65 (0.38) | .61 | .87 | .43 |
| BOT-2 total motor scoreb | 34.63 (0.47) | 35.05 (0.47) | 34.35 (0.43) | .53 | .65 | .27 |
| CogState, maze chase** correct moves per second | 0.47 (0.02) | 0.48 (0.02) | 0.31 (0.02) | <.01 | <.01 | <.01 |
| CogState, maze learning** correct moves per second | 0.25 (0.01) | 0.23 (0.01) | 0.15 (0.01) | <.01 | <.01 | <.01 |
| CogState, detection time* card turned (log msec) | 2.83 (0.01) | 2.84 (0.01) | 2.86 (0.01) | .13 | .05 | .21 |
| CogState, identification red card turned (log msec) | 2.97 (0.01) | 2.98 (0.01) | 2.97 (0.01) | .65 | .81 | .50 |
| CogState, accuracy in one-card learning | 0.63 (0.02) | 0.60 (0.02) | 0.61 (0.02) | .36 | .31 | .67 |
| CogState, accuracy in one-back card memory | 0.74 (0.03) | 0.70 (0.03) | 0.74 (0.03) | .46 | .97 | .29 |
| BRIEF behavior regulation indexb | 45.05 (1.03) | 43.76 (1.07) | 44.90 (0.97) | .61 | .91 | .42 |
| BRIEF metacognition index | 46.42 (0.99) | 45.69 (1.03) | 45.44 (0.93) | .73 | .45 | .85 |
| BRIEF global executive composite index | 45.34 (0.97) | 44.87 (1.02) | 45.40 (0.90) | .91 | .97 | .69 |
| CBCL Externalizing Total | 56.77 (0.89) | 55.19 (0.92) | 54.88 (0.84) | .24 | .11 | .80 |
| CBCL Internalizing Total | 59.35 (0.92) | 56.69 (0.95) | 57.70 (0.87) | .11 | .18 | .42 |
| CBCL Total | 55.61 (0.83) | 53.46 (0.86) | 54.45 (0.78) | .18 | .29 | .38 |
a
Standardardized scores (using age-based norms).
b
T scores using age- and gender-based norms.
*
p < .05 for CCRT versus limited CCRT.
**
p < .01 for CCRT versus limited CCRT.
p-Values in bold are statistically significant.
SE, standard errors.