Table 5.
Summary of Longitudinal Models with Group by Biological Measure at Baseline Interaction: Slopes for Computerized Cognitive Rehabilitation Training Versus Control, Their Standard Errors, Adjusted for Age, Being on HAART at Intake, Socioeconomic Score, Home Score, Recruitment Location, KABC Learning and Delayed Recall Scores At Baseline, and Outcome Score at Baseline
| Neuropsychology outcomes | Viral load: coefficient for CCRT vs. control (SE), p-value | CD4: coefficient for CCRT vs. control (SE), p-value | CD4 activation: coefficient for CCRT vs. control (SE), p-value | CD8: coefficient for CCRT vs. control (SE), p-value | CD8 activation: coefficient for CCRT vs. control (SE), p-value |
|---|---|---|---|---|---|
| KABC-II sequential processing | 0.17 (0.24), .49 | −0.17 (0.09), .05 | 0.03 (0.27), .92 | 0.23 (0.09), .02 | −0.02 (0.12), .90 |
| KABC-II simultaneous processing | −0.24 (0.29), .42 | −0.12 (0.11), .28 | 0.09 (0.32), .77 | 0.11 (0.12), .36 | 0.13 (0.14), .36 |
| KABC-II learning | 0.27 (0.26), .30 | −0.15 (0.09), .13 | 0.24 (0.29), 0.41 | 0.16 (0.10), .13 | 0.12 (0.12), .37 |
| KABC-II knowledge | −0.50 (0.24) .04 | −0.01 (0.09), .91 | −0.37 (0.27), .17 | 0.03 (0.10), .78 | −0.27 (0.12), .02 |
| KABC-II planning | −0.41 (0.21), .06 | 0.14 (0.07), .07 | −0.40 (0.20), .06 | −0.16 (0.08), .06 | −0.28 (0.09), <.01 |
| KABC delayed recall | 0.13 (0.24), .58 | −0.11 (0.08), .21 | 0.33 (0.26), .21 | 0.12 (0.09), .21 | 0.09 (0.11), .43 |
| KABC nonverbal index | −0.21 (0.25), .39 | 0.04 (0.09), .63 | −0.02 (0.27), .93 | −0.05 (0.10), .65 | −0.14 (0.12), .24 |
| KABC mental processing index | −0.01 (0.15), .97 | −0.08 (0.05), .14 | −0.03 (0.17), .86 | 0.10 (0.06), .10 | 0.00 (0.07), .94 |
| TOVA% omission errors | −0.16 (0.53), .77 | 0.34 (0.19), .07 | −0.49 (0.58), .40 | −0.33 (0.21), .12 | −0.18 (0.25), .49 |
| TOVA% commission errors | 0.19 (.32), .55 | 0.20 (0.11), .07 | 0.01 (0.35), .98 | −0.19 (0.13), .13 | −0.06 (0.15), .69 |
| TOVA response time | 0.58 (3.25), .86 | 1.04 (1.17), .38 | −3.33 (3.51), .34 | −0.73 (1.29), .57 | −1.51 (1.52), 0.32 |
| TOVA response time variability | 0.12 (2.03), .95 | 0.86 (0.73), .24 | −2.13 (2.20), .33 | −0.63 (0.80), .43 | −0.64 (0.97), .51 |
| TOVA D prime signal detection | −0.01 (0.03), .65 | −0.02 (0.01), .07 | 0.02 (0.03), .64 | 0.03 (0.01), .12 | 0.0 (0.02), .79 |
| TOVA ADHD index | −0.04 (0.10), .70 | −0.03 (0.04), .35 | 0.11 (0.11), .32 | 0.02 (0.04), .67 | 0.01 (0.05), .87 |
| CogState, maze chase Correct moves per second | 0.04 (.004), .75 | −0.01 (0.002), .40 | 0.00 (0.01), .96 | 0.0 (0.01), .56 | 0.00 (0.01), .45 |
| CogState, maze learning correct moves per second | 0.05 (0.003), .19 | −0.001 (0.001), .36 | .000 (.003), .96 | 0.001 (0.001), .61 | 0.003 (0.002), .08 |
| CogState, detection time: playing card turning | −0.004 (.003), .15 | 0.002 (0.001), .04 | −0.006 (0.003), .05 | −0.003 (0.001), .03 | −.003 (0.001), .02 |
| CogState, identification time: red playing card turning | −0.004 (0.003), .09 | 0.002 (0.001), .05 | −0.004 (0.003), .20 | −0.002 (0.001), .05 | −.002 (0.001), .18 |
| CogState, accuracy in one-card learning | 0.003 (0.003), .88 | 0.001 (0.001), .72 | −0.005 (0.004), .23 | −0.002 (0.002), .30 | −0.003 (0.002), .19 |
| CogState, accuracy in one-back card memory | 0.06 (0.007), .48 | −0.003 (0.003), .22 | 0.006 (0.008), .45 | 0.001 (0.003), .61 | 0.005 (0.004), .19 |
p-Values in bold are statistically significant in terms of the bivariate relationship.