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. 2016 Aug 3;6:31076. doi: 10.1038/srep31076

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Copyright © 2016, The Author(s)

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(A) Remnant EFS-induced vasoconstriction after preincubation with phentolamine. Effect of preincubation with 0.1 mmol/L suramin on vasoconstrictor response induced by EFS in endothelium-denuded mesenteric segments from Sham-operated (SO, B) and liver cholestasis (LC, C) rats. Results (mean ± S.E.M.) were expressed as a percentage of the initial contraction elicited by KCl. n = 6-8 animals per group. *P < 0.05 (Fisher post hoc test) (D) Differences of area under the curve (dAUC) in the absence or presence of 0.1 mmol/L suramin. *P < 0.05 SO vs. LC rats (Student’s t-test). dAUC values are expressed as arbitrary units.