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. 2016 Aug 3;6:30668. doi: 10.1038/srep30668

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Schematic representation of the KIF21A (UniProt: Q7Z4S6) and KIF21B (UniProt: O75037) motors. Domains are indicated. Predicted coiled-coil and non-coiled-coil regions in the stalk are shown in orange and black, respectively. The regulatory coiled-coil region (rCC) and the neck region are highlighted by a box and in red, respectively. CFEOM1 mutations are indicated in different colors. Fragments are represented by black lines and the GCN4 coiled coil is shown in brown.