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. 2016 Aug 3;6:30668. doi: 10.1038/srep30668

Figure 3. The regulatory domain of KIF21A folds into an antiparallel coiled coil as revealed by X-ray crystallography and SAXS.

Figure 3

(a) Ribbon representation of the crystal structure of rCC1 showing a chain-swapped, antiparallel coiled-coil dimer. The two helices of the dimer are colored differently. Amino (N) and carboxy (C) termini are indicated. (b) Ribbon representation of the electrostatic interaction between R960 and E988 visible in the crystal structure of rCC1. The two helices of the dimer are colored as in panel a and the salt bridge distance is indicated. (c) Normalized distance distribution function for rCC1 (grey) and calculated distance distribution functions of the dimeric rCC1 crystal structure (rCC1-dimer, magenta) and rCC1-monomer (black). (d) Calculated scattering curve of rCC1 overlaid on the CRYSOL-derived scattering curves of rCC1-monomer and rCC1-dimer. (e) Two representative 90° rotated views of the rCC1-monomer model superimposed by Subcomb on the averaged and filtered DAMMIF model.