Figure 3. Increased expression of systemic ANXA1 is associated with an anti-inflammatory profile and the IL-6 pathway in the peripheral blood.

Plots present tendency lines and the association between ANXA1 and cytokines expression along the SIV infection (2, 10, 26wk), demonstrating the systemic immune activation leading to an anti-inflammatory profile. Spearman’s rank test was used to determine correlations between ANXA1 and cytokines with p value < 0.05.