Table 2. Patient Characteristics by Benign (Non-Atypia) versus Malignant (Invasive Cancer) Disease Status.
Variable | Total (N = 28) | Invasive Cancer (n = 15) | Benign non-atypia (n = 13) | p-value1 |
---|---|---|---|---|
Age | 0.001 | |||
Median (Range) | 60 (33–84) | 75 (44–84) | 49 (33–70) | |
Menopausal status, n (%) | 0.02 | |||
Pre-menopause | 8 (28.6%) | 2 (13.3%) | 6 (46.2%) | |
Peri-menopause | 2 (7.1%) | 0 | 2 (15.4%) | |
Post-menopause | 18 (64.3%) | 13 (86.7%) | 5 (38.5%) | |
BMI category, n (%) | 0.17 | |||
18.5–24.9 | 6 (21.4%) | 4 (26.7%) | 2 (15.4%) | |
25–29.9 | 13 (46.4%) | 8 (53.3%) | 5 (38.5%) | |
≥30 | 9 (32.1%) | 3 (20.0%) | 6 (46.2%) | |
Smoking status, n (%) | 0.28 | |||
Former smoker | 10 (35.7%) | 4 (26.7%) | 6 (46.2%) | |
Never smoker | 18 (64.3%) | 11 (73.3%) | 7 (53.8%) | |
Diabetes mellitus, n (%) | 0.63 | |||
No | 25 (89.3%) | 13 (86.7%) | 12 (92.3%) | |
Yes, NIDDM | 3 (10.7%) | 2 (13.3%) | 1 (7.7%) | |
Prior ipsilateral breast surgery, n (%) | 0.26 | |||
No | 27 (96.4%) | 14 (93.3%) | 13 (100%) | |
Yes | 1 (3.6%) | 1 (6.7%) | 0 | |
Parity, n (%) | 0.76 | |||
0 | 4 (14.3%) | 2 (13.3%) | 2 (15.4%) | |
1–3 | 19 (67.9%) | 10 (66.7%) | 9 (69.2%) | |
>3 | 5 (17.9%) | 3 (20.0%) | 2 (15.4%) | |
Breastfed ever, n (%) | 1.0 | |||
No | 12 (57.1%) | 8 (57.1%) | 4 (57.1%) | |
Yes | 9 (42.9%) | 6 (42.9%) | 3 (42.9%) | |
Missing | 7 | 1 | 6 | |
Family history of breast cancer, n (%) | 0.49 | |||
No | 17 (60.7%) | 10 (66.7%) | 7 (53.8%) | |
Yes | 11 (39.3%) | 5 (33.3%) | 6 (46.2%) | |
Distance of specimen from nipple, n (%) | 0.53 | |||
≤2 cm | 4 (14.3%) | 2 (13.3%) | 2 (15.4%) | |
>2 cm and ≤5 cm | 11 (39.3%) | 5 (33.3%) | 6 (46.2%) | |
>5 cm | 13 (46.4%) | 8 (53.3%) | 5 (38.5%) | |
Time from incision to sample collection, minutes | ||||
Median (range) | 69 (30–206) | 82 (54–206) | 52 (30–72) | <0.0001 |
1P-value was calculated using Wilcoxon rank-sum tests for continuous variables, chi-square tests for nominal variables, and Cochran-Armitage trend tests for ordinal variables.