Table 2. EC50 Values (pM) of Daclatasvir for NS5A Mutants in the Presence of Different Concentrations of LNA–anti-miR-122.
| Mutants | Concentrations of LNA-anti-miR-122 | |||||
|---|---|---|---|---|---|---|
| 0 nM | 0.5 nM | 1 nM | 5 nM | 8 nM | 10 nM | |
| WT | 18.8 | 13.2 | 17.0 | 15.4 | ND | 15.3 |
| Q30R | 4370.1 | 1133.4 | 975.1 | 696.4 | 1593.8 | 2230.9 |
| L31V | 9487.5 | 8250.2 | 3853.5 | 786.7 | 2332.2 | 5694.9 |
ND: not determined.