Figure 5. Mbnl3^ΔE2 mice demonstrate subcapsular and cortical cataracts.

(a,c) Fundus camera photographs of representative male Mbnl3^+/+ and male Mbnl3^ΔE2 mice at 7 months and 12 months of age respectively are shown. (b,d) Grade and location of cataracts in Mbnl3^+/+ and Mbnl3^ΔE2 mice at 7 months and 12 months are tabulated. Lenses were observed using a Haag Streit 900 slit lamp and cataracts were evaluated using the LOCS II photographic grading standards. Mann-Whitney U test demonstrates a statistically significant difference in cataract grade between Mbnl3^+/+ and Mbnl3^ΔE2 mice at 12 months of age (p = 0.001).