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. 2016 Aug 3;6:30964. doi: 10.1038/srep30964

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Copyright © 2016, The Author(s)

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(A) Passive IgAN mice were intravenously delivered indicated amount of IgA protease from H. influenzae 49247 or PBS 6-hour post model construction. The mice (n = 5 for each group) were sacrificed 2 hours later and relative fluorescent intensity of residual immune complexs was plotted. Data represents 20 glomeruli on 10 sections of 5 mice each group. **P < 0.01 for both IgA Fab and IgG Fab. ns, no significance for both IgA Fab and IgG Fab. (B) Representative images of immunofluorescence of human IgA1 Fc, Fab (green) and goat IgG Fab (red) fragment in passive IgAN mice treated with 15 μg of H. influenzae 49247 IgA protease.