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The diagram of Chr19 domain upstream of the p85 gene. A 347 bp region upstream of the p85 gene of human chromosome 19 was investigated for transcriptional regulation. Two sites involved in AAV integration are also depicted; (i) the terminal resolution site (TRS) and (ii) the AAV Rep protein-binding element (RBE). Primers used for genetic dissection of this region are also shown (F = forward, R = reverse). AAV, adeno-associated virus.
