Table 2.

TEAE reported by participants at postmedication assessments.

Study visit	Total number reporting TEAE	TEAE details (number reported)
2 weeks	14	Sweating (6), heartburn (2), dry mouth (2), nausea (6), decreased appetite at night (2), hot flushes (2), irritability (2), light headedness (2), headache (3), drowsiness and diarrhoea for 3 days, insomnia for 4 days
4 weeks	12	Sweating (5), headache (3), nausea (2), dry mouth (2), muscle tension, hot flushes when not taken with food, light headedness, drowsiness/tiredness at night after meds, nausea for 1 day
6 weeks	6	Sweating (3), headache (4), dry mouth (2), tiredness, hot flushes, low appetite in pm
8 weeks	6	Nausea as a result of increased exercise, dry mouth (3), sweating (4), headache (3)
10 weeks	6	Mild sweating, headache (2), dry mouth (2), nausea for few hours after meds, night sweating since increase to 100 mg
12 weeks	8	Sweating (3), headaches occasional, hot flushes, nausea after meds

TEAE, treatment-emergent adverse effect.