Table 1.
Baseline characteristics of the study population
| Characteristics | eGFR | p value | ||
|---|---|---|---|---|
| Total | <60 mL/min | ≥60 mL/min | ||
| No. of patients | n = 2989 | n = 506 | n = 2483 | |
| Age, years | 64.5 ± 10.6 | 70.4 ± 8.0 | 63.3 ± 10.7 | <0.001 |
| Gender, female, n (%) | 614 (20.5) | 162 (32.0) | 452 (18.2) | <0.001 |
| Body composition parameters | ||||
| BMI, kg/m2 | 24.2 ± 2.9 | 24.1 ± 2.8 | 24.2 ± 2.9 | 0.477 |
| BF, % | 28.1 ± 6.2 | 30.2 ± 6.6 | 27.7 ± 6.0 | <0.001 |
| LMI, kg/m2 | 17.3 ± 1.8 | 16.7 ± 1.9 | 17.4 ± 1.8 | <0.001 |
| Medical history | ||||
| Current smoking, n (%) | 902 (30.2) | 151 (29.8) | 751 (30.2) | 0.857 |
| Pre-hypertension, n (%) | 1628 (54.5) | 352 (69.6) | 1276 (51.4) | <0.001 |
| Pre-diabetes mellitus, n (%) | 653 (21.8) | 154 (30.4) | 499 (20.1) | <0.001 |
| At admission | ||||
| Systolic blood pressure, mm Hg | 130.3 ± 21.2 | 132.0 ± 24.1 | 129.9 ± 20.6 | 0.059 |
| Diastolic blood pressure, mm Hg | 76.3 ± 12.5 | 74.2 ± 13.4 | 76.7 ± 12.3 | <0.001 |
| Heart rate, beats/min | 74.1 ± 13.9 | 76.3 ± 16.1 | 73.6 ± 13.4 | 0.001 |
| Killip classification ≥ II, n (%) | 344 (11.5) | 93 (18.4) | 251 (10.1) | <0.001 |
| Laboratory values | ||||
| eGFR, ml/min/1.73 m2 | 79.5 ± 22.9 | 45.9 ± 12.4 | 86.3 ± 18.0 | <0.001 |
| Blood glucose, mmol/L | 6.9 ± 3.1 | 7.7 ± 4.1 | 6.8 ± 2.8 | <0.001 |
| Total cholesterol, mmol/L | 4.1 ± 1.1 | 4.0 ± 1.1 | 4.1 ± 1.1 | 0.222 |
| Diagnosis | ||||
| ACS, n (%) | 2163 (72.4) | 382 (75.5) | 1781 (71.7) | 0.084 |
| UA, n (%) | 1533 (51.3) | 257 (50.8) | 1276 (51.4) | 0.806 |
| Severity of CAD | ||||
| Left main artery, n (%) | 282 (9.4) | 54 (10.7) | 228 (9.2) | 0.296 |
| Three vessel diseases, n (%) | 758 (25.4) | 176 (34.8) | 582 (23.4) | <0.001 |
| Discharge medication | ||||
| Aspirin, n (%) | 2760 (92.3) | 432 (85.4) | 2328 (93.8) | <0.001 |
| Clopidogrel, n (%) | 2670 (89.3) | 428 (84.6) | 2242 (90.3) | <0.001 |
| Statin, n (%) | 2678 (89.6) | 432 (85.4) | 2246 (90.5) | 0.001 |
| ACE inhibitors or ARBs, n (%) | 1702 (56.9) | 290 (57.3) | 1412 (56.9) | 0.854 |
| Beta-receptor blockers, n (%) | 1981 (66.3) | 301 (59.5) | 1680 (67.7) | <0.001 |
Data are expressed as mean ± SD or counts and percentages, as appropriate
BMI body mass index; BF body fat; LMI lean mass index; eGFR estimated glomerular filtration rate; ACS acute coronary syndrome; UA unstable angina; CAD coronary artery disease; ACE angiotensin-converting enzyme; ARBs angiotensin-receptor blockers