Table 2.
HLA 10/10 | HLA 9/10 | HLA 8/10 | p value | |
---|---|---|---|---|
Total number of patients | 2567 | 723 | 108 | |
Engraftment, n (%) | 2458 (97.3 %) | 678 (96.3 %) | 101 (97.12 %) | 0.313 |
No engraftment, n (%) | 67 (2.7 %) | 26 (3.7 %) | 3 (2.9 %) | |
Missing, n | 42 | 19 | 5 | |
Median time ANC >0.5 G/L (days, range) | 16 (0–103) | 16 (1–165) | 15.5 (1–33) | 0.538 |
Acute GVHD, | ||||
Grade 0–I, n (%) | 1826 (74.4 %) | 469 (67.2 %) | 67 (65.7 %) | 0.0002 |
Grades II–IV, n (%) | 629 (25.6 %) | 229 (32.8 %) | 35 (34.3 %) | |
Grades III–IV, n (%) | 234 (9.5 %) | 90 (12.9 %) | 11 (10.8 %) | 0.035 |
Missing, n | 75 | 21 | 3 | |
Chronic GVHDa | ||||
All grades | 35.0 % [32.9–37.2] | 35.1 % [31.2–39] | 44.4 % [33.6–54.6] | 0.138 |
Extensive | 17.1 % [15.4–18.9] | 15.2 % [12.3–18.5] | 26.1 % [16.8–36.4] | 0.047 |
Limited, n | 369 | 109 | 14 | |
Extensive, n | 324 | 80 | 21 | |
Missing, n | 38 | 18 | 5 |
GVHD graft-versus-host disease
aTwo-year cumulative incidence