Table 4.
Causes of death according to donor HLA matching
| HLA 10/10 | HLA 9/10 | HLA 8/10 | |
|---|---|---|---|
| Relapse | 552 (47.5 %) | 173 (43.4 %) | 21 (36.2 %) |
| Infection | 249 (21.3 %) | 100 (25.1 %) | 21 (36.2 %) |
| GVHD | 202 (17.3 %) | 80 (20.1 %) | 10 (17.2 %) |
| Graft failure/rejection | 11 (0.9 %) | 1 (0.3 %) | 0 |
| Cardiac toxicity | 8 (0.7 %) | 4 (1 %) | 1 (1.7 %) |
| Haemorhage | 14 (1.2 %) | 5 (1.3 %) | 1 (1.7 %) |
| VOD | 12 (1 %) | 8 (2 %) | 0 |
| Idiopathic pneumonia | 25 (2.1 %) | 9 (2.3 %) | 0 |
| Second malignancy | 24 (2.1 %) | 5 (1.3 %) | 0 |
| Other SCT-related | 70 (6 %) | 14 (3.5 %) | 4 (6.9 %) |
GVHD graft-versus-host disease, SCT stem cell transplantation, VOD veno-occlusive disease