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. 2016 Aug 2;16:583. doi: 10.1186/s12885-016-2569-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — TUG1 expressions in NSCLC lung tissues. a TUG1 was examined in 89 pairs of NSCLC tumor and nontumor tissues through qRT-PCR. Fold changes in TUG1 expression were demonstrated, revealing significant downregulation of TUG1 in tumor tissues. b Log2 fold changes in TUG1 expressions (T/N) of each case are plotted. c–e TUG1 expression levels were significantly lower in male patients, smokers, and those with poor-differentiation tumors (*p < 0.05, **p < 0.01). f Survival curves for patients with TUG1 downregulation (n = 58) and TUG1 upregulation (n = 31)