Skip to main content

View full-text article in PMC

. 2016 Aug 2;16:589. doi: 10.1186/s12885-016-2637-y

Table 4.

Univariate^b and multivariate survival^a analysis in type I and type II cancers for LINE1 DNA hypomethylation

			Univariate						Multivariate
			PFS			OS			PFS			OS
			Months	CI 95 %	p value	Months	CI 9 5%	p value	HR	CI 95 %	p value	HR	CI 95 %	p value
Type I	LINE1 DNA hypomethylation^c	Low	208.9	154.8-262.8	0.011*	197.62	148.2-247.1	0.006**	6.13	1.24-30.22	0.026*	6.82	1.53-30.39	0.012*
	LINE1 DNA hypomethylation^c	High	48.1	18.7-77.5	0.011*	67.9	24.5-111.3	0.006**	6.13	1.24-30.22	0.026*	6.82	1.53-30.39	0.012*
	Grading	G1 VS G2-3							2.87	0.65-12.65	0.164	1.64	0.43-6.18	0.467
	FIGO stage	I-II VS III-IV							1.98	0.21-18.69	0.549	1.09	0.07-16.16	0.949
	Age	< o > median							0.61	0.11-3.27	0.566	3.84	1.09-13.52	0.036*
	Residual disease	0 VS >0							5.16	2.76-9.64	<0.0001**	21.6	1.23-377.66	0.035*
Type II	LINE1 DNA hypomethylation^c	low	51.4	15.0-87.8	0.791	86.10	38.7-133.5	0,878
Type II	LINE1 DNA hypomethylation^c	high	42.7	15.7-69.8	0.791	68.97	38.9-98.9	0,878

*Significant at the 0.05 level, **Significant at the 0.01 level, ^alog rank test, ^bCOX-regression analysis; ^cPUMR values