Table 1.
TIMP-1 Immunoreactivity in Gastric Cancer According to Histological Subtype and TNM Stage.
| Parameter | Total | Intestinal | Diffuse |
|---|---|---|---|
| Total number of cases | 49 | 25 | 24 |
| Cases according to TNM stage | |||
| I | 5 | 2 | 3 |
| II | 10 | 5 | 5 |
| III | 15 | 6 | 9 |
| IV | 19 | 12 | 7 |
| Cases according to TIMP-1-positive cell type | |||
| Myofibroblasts, tumor invasion front | 35 | 22 | 13 |
| Myofibroblasts, tumor central areas | 22 | 13 | 9 |
| Myofibroblasts, tumor luminal side | 16 | 10 | 6 |
| Cancer cells | 9 | 4 | 5 |
| Neuroendocrine cells | 39 | 20 | 19 |
| Cases with TIMP-1-positive myofibroblasts tumor invasion front according to TNM stage | |||
| I | 2 | 1 | 1 |
| II | 6 | 4 | 2 |
| III | 11 | 6 | 5 |
| IV | 16 | 11 | 5 |
Abbreviation: TIMP-1, tissue inhibitor of metalloproteinase-1; TNM, tumor, node, metastasis.