Fig. 3.
Effect of dibutyryl cAMP (db-cAMP) and subsequent addition of luminal ANG II on chloride transport in the mTAL. After measurement of chloride transport in the control period, 10−3 M db-cAMP was added to the bathing solution, which resulted in an increase in mTAL chloride transport (P < 0.05). Addition of 10−8 M ANG II in the presence of bath db-cAMP resulted in a further stimulation in chloride transport (P < 0.05, all tubules). Dashed lines represent chloride transport in individual tubules, the dark line represents the mean and SE of all tubules.