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. 2015 Dec 23;310(5):C390–C400. doi: 10.1152/ajpcell.00091.2015

Fig. 9.

Fig. 9.

PICK1/Calcineurin inhibit PKA-stimulated SOCE. SOCE responses were determined by AUC in PASMC pretreated with the PICK1 inhibitor FSC231 (50 μM), calcineurin inhibitor cyclosporin A (CsA; 1 μM), ASIC1 inhibitor psalmotoxin 1 (PcTX1; 20 nM), PKA activator forskolin (10 μM), or PKA inhibitor KT 5720 (300 nM) as indicated on graphs. Values are means ± SE; n = 4–6/group. A: *P < 0.05 vs. vehicle; #P < 0.05 vs. FSC231/CsA. B: *P < 0.05 vs. non-FSC231/CsA treatment and #P < 0.05 vs. non-forskolin or -KT 5720 treatment; analyzed with one-way (A) or two-way (B) ANOVA and individual groups compared with the Student-Newman-Keuls test.