Table 1.
Relationship between CHIP expression, biomarkers, and histological grade
| CHIP | Score 0 | Score 1 | Score 2 | Score 3 | P | All (n = 272) |
|---|---|---|---|---|---|---|
| Histological grade | ||||||
| Grade 3 | 36 | 51 | 40 | 27 | 0.044 | 154 |
| Grade 1/2 | 13 | 40 | 43 | 22 | 118 | |
| ER | ||||||
| Negative (<1%) | 34 | 25 | 15 | 7 | <0.001 (−2.07E‐10) | 81 |
| Positive (≥1%) | 15 | 66 | 68 | 42 | 191 | |
| PgR | ||||||
| Negative (<1%) | 34 | 32 | 23 | 16 | <0.001 (0.00016) | 105 |
| Positive (≥1%) | 15 | 59 | 60 | 33 | 167 | |
| HER2 | ||||||
| Negative | 34 | 78 | 72 | 44 | 0.022 | 228 |
| Positive | 15 | 13 | 11 | 5 | 44 | |
ER, estrogen receptor; PgR, progesterone receptor; HER2, human epidermal growth factor receptor 2.