Table 1.
ROTEM tests | Reagents used | Description |
---|---|---|
EXTEM | Tissue factor activator | Coagulation is activated by small amount of tissue factor to monitor coagulation via extrinsic pathway |
INTEM | Ellagicacid/phospholipid activator | Coagulation is activated by contact phase to monitor coagulation via intrinsic pathway |
HEPTEM | Heparinase in combination with INTEM | Comparison of HEPTEM with INTEM parameters can help in detection of heparinrelated coagulation disturbances |
FIBTEM | Cytochalasin D in combination with EXTEM | Coagulation is activated as in EXTEM after neglecting platelet contribution to the clot firmness |
APTEM | Aprotinin, fibrinolysis inhibitor in combination with EXTEM | Coagulation is activated as in EXTEM to monitor the clot firmness after blocking hyperfibrinolysis by aprotinin |
ECATEM | Ecarin (prothrombin activator) | Diagnose direct thrombin inhibitor |
NATEM | Activated by recalcification only | Sensitive to detect endogenous activators like tissue factor expression on monocytes cells in sepsis, extracorporeal device use, cirrhosis |
ROTEM: Rotational thromboelastometry