Skip to main content
. 2016 Jul-Sep;19(3):516–520. doi: 10.4103/0971-9784.185546

Table 1.

Various rotational thromboelastometry tests with different reagents

ROTEM tests Reagents used Description
EXTEM Tissue factor activator Coagulation is activated by small amount of tissue factor to monitor coagulation via extrinsic pathway
INTEM Ellagicacid/phospholipid activator Coagulation is activated by contact phase to monitor coagulation via intrinsic pathway
HEPTEM Heparinase in combination with INTEM Comparison of HEPTEM with INTEM parameters can help in detection of heparinrelated coagulation disturbances
FIBTEM Cytochalasin D in combination with EXTEM Coagulation is activated as in EXTEM after neglecting platelet contribution to the clot firmness
APTEM Aprotinin, fibrinolysis inhibitor in combination with EXTEM Coagulation is activated as in EXTEM to monitor the clot firmness after blocking hyperfibrinolysis by aprotinin
ECATEM Ecarin (prothrombin activator) Diagnose direct thrombin inhibitor
NATEM Activated by recalcification only Sensitive to detect endogenous activators like tissue factor expression on monocytes cells in sepsis, extracorporeal device use, cirrhosis

ROTEM: Rotational thromboelastometry