Table 1.
Characteristics at ICU admission of 103 patients with cancer with acute renal failure requiring renal replacement therapy.
| Sex (male/female) | 69/34 (67%/33%) |
| Age (median/range) | 62 years (19–87) |
| Solid malignancies (locoregional/metastatic) | 68 (66%) (28/40) |
| Breast | 7 (7%) |
| Lung | 6 (6%) |
| Digestive tract | 15 (15%) |
| Prostate/bladder/kidney | 23 (22%) |
| Other | 17 (17%) |
| Hematological malignancies | 35 (34%) |
| Leukemia | 10 (10%) |
| Lymphoma | 14 (14%) |
| Multiple myeloma | 9 (9%) |
| Myelodysplastic syndrome | 2 (2%) |
| Stem cell transplantation before ICU admission (allo/auto) | 18 (14/4) (17%) |
| Cancer phase | |
| Diagnostic | 9 (9%) |
| Curative | 41 (40%) |
| Controllable | 53 (51%) |
| Cancer status | |
| Induction | 25 (24%) |
| Diagnostic | 9 (9%) |
| Remission (partial or complete) | 35 (34%) |
| Stabilization | 1 (1%) |
| Progression | 33 (32%) |
| Causes of ICU admission | |
| Renal disease | 58 (56%) |
| Shock/sepsis | 20 (19%) |
| Metabolic disorder | 9 (9%) |
| Respiratory failure | 8 (8%) |
| Other | 8 (8%) |
| Chemotherapy given before ICU admission | |
| Less than 15 days | 35 (34%) |
| More than 15 days | 27 (26%) |
| No | 41 (40%) |
| Immunodepression | 50 (49%) |
| Urinary tract infection | 14 (14%) |
| Diabetes | 14 (14%) |
| Baseline characteristics at the time of initiation of CVVHDF | |
| ARDS | 25 (24%) |
| Mechanical ventilation | 53 (51%) |
| Vasopressors | 43 (42%) |
| Hematological failure | 28 (27%) |
| >1 organ failure | 65 (63%) |
| pH (median/range) | 7.3 (7.02–7.52) |
| Natremia (mEq/l) (median/range) | 138 (122–150) |
| Kaliemia (mEq/l) (median/range) | 4.7 (2.9–8) |
| Creatininemia (mg/dl) (median/range) | 3.76 (1.28–20.1) |
| Uremia (mg/dl) (median/range) | 151 (49–492) |
| SAPS II (median/range) | 56 (28–99) |
ICU, intensive care unit; SAPS, simplified acute physiology score; allo, allogenic; auto, autologous; ARDS, acute respiratory distress syndrome.