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. 2016 Feb 12;35(8):820–830. doi: 10.15252/embj.201593285

Figure 1. Patch‐clamp measurements of the ion selectivity of wild‐type and E178 mutant NavMs channels.

Figure 1

  1. Left: Representative current traces from wild‐type NavMs channels showing the first 0.1 s of 0.5 s activations from −180 mV holding potential recorded with the indicated extracellular cations. Right: Resulting current–voltage profiles, where current magnitudes were normalised to the maximum inward current measured in the sodium condition (error ± SEM; n = 6–9).
  2. Left: Representative current traces from mutant channel E178D (as in A). Right: Resulting current–voltage profiles (error ± SEM; n = 4–8).