Table 6. Genes of core enrichment in the apoptosis pathway of different experimental groups.

Both of the DMSO vs. no light conditions produced an increase in expression of all of the listed genes in the first condition compared to the second. All other conditions produced a decrease in expression of all of the listed genes. In particular, the “DMSO vs. no light” columns represented controls for each set of experiments and DMSO induced an increase in the expression of the listed genes compared with the no light control.

DMSO vs. no light	BRM vs. DMSO	MTP vs. DMSO	TAM vs. DMSO	DOX vs. DMSO	DMSO vs. no light*	BRM + MTP + TAM vs. DMSO	BRM + MTP + DOX vs. DMSO
Fas	Myd88	Fas	Bid	Fas	Myd88	Myd88	Tnfrsf1a
Ripk1	Ripk1	Myd88	Il1r1	Myd88	Tnfrsf1a	Fas	Myd88
Myd88	Il1r1	Bid	Tnfrsf1a	Il1r1	Il1r1	Tnfrsf1a	Ripk1
Il1r1	Tnfrsf1a	Ripk1	Casp6	Ripk1	Ripk1	Ripk1	Fas
Tnfrsf1a	Bid	Il1r1	Tradd	Trp53	Irak1	Il1r1	Il1r1
Bid	Trp53	Trp53	Myd88	Tnfrsf1a	Rela	Ntrk1	Prkx
Trp53	Prkx	Tnfrsf1a	Trp53	Tradd	Trp53	Trp53	Rela
Capn2	Fas	Prkx	Akt2	Tnfrsf10b	Bid	Bid	Map3k14
Prkx	Tradd	Capn2	Fas	Irak1	Akt2	Rela	Trp53
Apaf1	Casp3	Irak2	Ripk1	Bid	Prkx	Map3k14	Ntrk1
Tradd	Apaf1	Casp6	Il1rap	Chuk	Fas	Traf2	Bid
Casp6	Irak1	Nfkbia	Casp3	Casp3	Map3k14	Akt2	Akt2
Ntrk1	Birc2	Tradd	Rela	Casp6	Ntrk1	Bax	Irak1
Tnfrsf10b	Ikbkb	Il1rap	Ntrk1	Il1rap	Tradd	Nfkbia	Ikbkb
Il1rap	Nfkbia	Rela	Irak2	Apaf1	Apaf1	Prkx	Bax
Prkar2b	Ntrk1	Irak1	Nfkb1	Capn2	Nfkbia	Bcl2l1	Apaf1
Irak1	Il1rap	Casp3	Nfkbia	Prkar2b	Tnfrsf10b	Tnfrsf10b	Casp3
Rela	Capn2	Akt2	Capn2	Prkx	Capn2	Irak1	Nfkbia
Casp3	Rela	Ntrk1	Prkar2b	Nfkbia	Akt1	Bad	Traf2
Nfkbia	Pik3cb			Irak2	Bax	Akt1	Bcl2l1
	Chuk			Pik3cb	Traf2	Tradd	Aifm1
				Ppp3ca	Il1rap	Irak2	Pik3r3
				Prkacb		Capn1
						Capn2

^*The controls are from two separate experiments (single and combined treatment) that were performed. Each experiment has its own control and light-exposed mice. The differences represent the variation of light damage from one experiment to the other.