Table 1.
Case # | Age (years) | Sex | Side of hemiparesis | Etiology | Time since injury (months) | Prior treatment | Dose injected (IU)/# sites | Dose per weight IU/kg | Muscles injected | Compliance with exercise program |
---|---|---|---|---|---|---|---|---|---|---|
1 | 67 | Male | Right | Ischemic stroke | 29 | Botulinum Toxin | 450/6 | 5.09 | Pectoralis minor, triceps, pronator teres, flexor carpi radialis, extensor carpi ulnaris, extensor digitorum communis | Non-compliant |
2 | 48 | Female | Right | Hemorrhagic stroke | 64 | Botulinum Toxin | 450/6 | 8.65 | Pectoralis minor, pronator teres, flexor carpi radialis, extensor carpi ulnaris, flexor digitorum, extensor digitorum communis | Non-compliant |
3 | 59 | Male | Left | Ischemic stroke | 61 | Botulinum Toxin | 450/6 | 5.51 | Pectoralis minor, pronator teres, flexor carpi radialis, extensor carpi ulnaris, flexor digitorum, extensor digitorum communis | Compliant |
4a | 53 | Female | Left | Hemorrhagic stroke | 54 | Botulinum Toxin | 450/7 | 5.10 | Pectoralis minor, biceps brachi, pronator teres, flexor carpi radialis, extensor carpi ulnaris, extensor digitorum communis, abductor pollicis | Non-compliant |
5a | 66 | Male | Right | Hemorrhagic stroke | 41 | Botulinum Toxin | 450/6 | 4.10 | Pectoralis minor, biceps brachi, pronator teres, flexor carpi radialis, extensor carpi ulnaris, extensor digitorum communis | Non-compliant |
6 | 43 | Female | Left | Ischemic stroke | 45 | None | 450/6 | 7.87 | Pectoralis minor, brachialis, pronator teres, flexor digitorum, extensor digitorum communis, palmar aponeurosis | Compliant |
7 | 43 | Male | Right | Ischemic stroke | 10 | Botulinum Toxin | 600/8 | 7.08 | Pectoralis minor, teres major, pronator teres, flexor carpi radialis, extensor carpi ulnaris, flexor digitorum, extensor digitorum communis, palmar aponeurosis | Compliant |
8 | 59 | Male | Right | Ischemic stroke | 24 | Botulinum Toxin | 600/8 | 6.58 | Pectoralis minor, teres major, pronator teres, flexor carpi radialis, extensor carpi ulnaris, extensor digitorum communis, flexor digitorum, palmar aponeurosis | Compliant |
9a | 64 | Male | Right | Hemorrhagic stroke | 85 | None | 600/8 | 7.16 | Pectoralis minor, biceps brachi, pronator teres, flexor carpi radialis, extensor carpi ulnaris, flexor digitorum, extensor digitorum communis, palmar aponeurosis | Compliant |
10 | 15 | Male | Right | Ischemic stroke (carotid dissection) | 5 | None | 600/8 | 10.24 | Pectoralis minor, biceps brachi, brachialis, pronator teres, flexor carpi ulnaris, flexor digitorum, extensor digitorum communis, palmar aponeurosis | Compliant |
11 | 11 | Female | Left | Cerebral palsy | 114 | Botulinum Toxin | 450/7 | 14.66 | Pectoralis major, biceps brachi, pronator teres, flexor carpi ulnaris, extensor carpi radialis, flexor digitorum, palmar aponeurosis | Non-compliant |
12 | 38 | Female | Right | Ischemic stroke | 18 | None | 600/8 | 9.84 | Pectoralis minor, biceps brachi, brachialis, pronator teres, flexor carpi ulnaris, flexor digitorum, extensor digitorum communis, palmar aponeurosis | Compliant |
13a | 10 | Male | Right | Cerebral palsy | 152 | Botulinum Toxin | 300/6 | 5.55 | Pectoralis minor, biceps brachi, flexor carpi radialis, flexor carpi ulnaris, flexor digitorum, extensor digitorum communis | Non-compliant |
14 | 39 | Male | Left | Hemorrhagic stroke | 35 | Botulinum Toxin | 450/9 | 6.94 | Pectoralis minor, biceps brachi, brachialis, pronator teres, flexor carpi ulnaris, extensor digitorum communis, palmar aponeurosis, interosseus III-IV and IV-V | Compliant |
15 | 11 | Male | Right | Brain tumor resection | 8 | None | 450/9 | 10.54 | Pectoralis minor, biceps brachi, flexor carpi ulnaris, flexor carpis radialis, flexor digitorum, extensor digitorum communis, palmaris aponeurosis, interosseus III-IV and IV-V | Compliant |
16 | 10 | Female | Right | Stroke (AVM rupture) | 17 | None | 300/5 | 10.38 | Pronator teres, brachialis, extensor carpi ulnaris, flexor digitorum, hypothenar eminence | Compliant |
17 | 15 | Female | Right | Brain tumor resection | 13 | Botulinum Toxin | 600/9 | 9.48 | Levator scapula, pectoralis minor, biceps brachi, brachioradialis, pronator teres, flexor carpi ulnaris, extensor carpi radialis, flexor digitorum, extensor digitorum communis, palmar aponeurosis | Compliant |
18 | 58 | Male | Right | Hemorrhagic stroke | 12 | None | 600/8 | 8.10 | Romboid minor, pectoralis minor, biceps brachi, brachialis, pronator teres, flexor carpi ulnaris, flexor digitorum, extensor digitorum communis | Non-compliant |
19a | 77 | Male | Left | Ischemic stroke | 19 | None | 450/5 | 4.72 | Posterior deltoid, pectoralis minor, pronator teres, flexor carpi radialis, extensor digitorum communis | Compliant |
20 | 37 | Male | Right | Radiation-induced vasculitis | 7 | Botulinum Toxin | 600/9 | 8.82 | Levator scapula, pectoralis minor, brachialis, pronator teres, flexor carpi ulnaris, flexor digitorum, extensor digitorum communis, abductor pollicis, palmar aponeurosis | Compliant |
Patients that did not receive subsequent hyaluronidase injections.