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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Clin Ther. 2015 Nov 11;38(1):162–179.e6. doi: 10.1016/j.clinthera.2015.10.010

Table 3.

Results of the Egger test

Results Change in
IRLS		 Responder rates
for IRLS		 Responder rates
for CGI-I		 Responder rates
for PGI		 Change in
quality of life		 Change in
daytime tiredness		 Change in
PLMS		 Change in
quality of sleep
P value 0.364 0.110 0.226 0.228 0.768 0.663 0.795 0.017
Interval
(95% CI)		 −9.16 to
3.89		 −0.50 to 3.78 −1.50 to 5.57 −1.95 to 6.90 −76.59 to 65.45 −9.91 to 7.83 −48.67 to
46.19		 0.99 to 5.71

RLS: Restless Legs Syndrome; IRLS: International RLS Study Group Rating Scale; CGI-I: Clinical Global Impression of Improvement scale; PGI: Patient Global Impression scale; PLMS: Periodic limb movements in sleep per hour of sleep

RR is used as an effect size index for binary variables, and WMD is used as an effect size index for continuous variables.