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. Author manuscript; available in PMC: 2016 Oct 11.
Published in final edited form as: Bone Marrow Transplant. 2016 Apr 11;51(8):1107–1112. doi: 10.1038/bmt.2016.63

Table 3.

Risk factors for Grade II-IV aGVHD

Risk Factor N Cumulative Incidence 95% CI P-value
Age (years) <20 32 22% 8- 36% <0.01
20-40 25 16% 2- 30%
≥40 63 46% 33- 59%

Sex Male 69 36% 25- 48% 0.45
Female 51 29% 17- 42%

Malignant Disease Yes 96 39% 28- 49% 0.01
No 24 13% 0- 25%

Previous aGVHD Yes 61 39% 27- 52% 0.32
No 59 27% 16- 39%

Previous chronic GVHD Yes 44 43% 28- 58% 0.11
No 76 28% 17- 38%

Chemo-DLI Yes 37 59% 42- 77% <0.01
No 83 22% 13- 31%

Time from HCT to DLI (days) <200 45 44% 29- 60% 0.01
≥200 75 27% 17- 37%

Donor Type Sibling 83 30% 20- 40% 0.29
URD 37 41% 24- 57%

DLI Dose (CD3 /kg) <1×107 27 19% 4- 33% 0.23
1×107-1×108 65 35% 23- 47%
≥1×108 28 43% 24- 62%