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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Chem Phys Lipids. 2016 May 11;199:136–143. doi: 10.1016/j.chemphyslip.2016.05.003

Figure 1.

Figure 1

Cholesterol has multiple effects on lipid bilayers. Cholesterol (a) changes the fluidity (b), thickness (c), compressibility (d), water penetration (e), and intrinsic curvature (f) of lipid bilayers. Cholesterol also induces phase separations in multicomponent lipid mixtures (g), partitions selectively between different coexisting lipid phases (h), and causes integral membrane proteins to respond by changing conformation (i) or redistribution (j) in the membrane.