Skip to main content
. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Mol Neurobiol. 2016 Feb 3;54(2):1392–1403. doi: 10.1007/s12035-016-9746-0

Fig. 3.

Fig. 3

miR-196a expression in ABCD1-silenced U87 astrocytes and B12 oligodendrocytes. Human U87 astrocytes cells and rat B12 oligodendrocyte cells were transduced with ABCD1 Lentiviral (ABCD1-Lenti) shRNA particles followed by selection with puromycin. There was significant decrease in ABCD1 expression as analysed by qRT-PCR (a and b). **P < 0.05 vs. WT. Similar to cALD cells/brain, miR-196a expression was downregulated in both ABCD1-silenced U87 and B12 (c and d). An unpaired student t test was used to determine the statistical significance of the data from three independent experiments