Table 1.

Brain disorders associated with brain iron accumulation or brain iron deficiency

Brain iron accumulation	Brain iron deficiency
Neurodegeneration with brain iron accumulation (Forni et al. 2008)	Restless legs syndrome (Allen and Earley 2001; Connor et al. 2011)
Hemochromatosis (Bartzokis et al. 2010)	Hypomyelination (Beard and Connor 2003)
Amyotrophic lateral sclerosis (Oba et al. 1993)
Parkinson’s disease (Connor et al. 1995)
Alzheimer’s disease (Connor et al. 1995)
Huntington’s disease (Zecca et al. 2004)