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Charge profiles: comparison of ABP 501 (red line), adalimumab (US) (black line), and adalimumab (EU) (blue line) for carboxypeptidase B-treated cation exchange-high performance liquid chromatography profiles (a) and intact capillary isoelectric focusing profiles (b). Adalimumab (EU) European Union-authorized adalimumab, adalimumab (US) United States Food and Drug Administration-licensed adalimumab, AU absorbance units, pI isoelectric points, mAU milli absorbance units
