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. 2016 Jul 4;5(7):e239. doi: 10.1038/oncsis.2016.46

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Copyright © 2016 Macmillan Publishers Limited

Oncogenesis is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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IHC expression of Nm23H1 and CLDN1 in human adjacent non-tumor mucosa and ESCC. (a) Nm23H1 and CLDN1 (arrowheads) in tumor-adjacent normal esophageal tissues counterstaining with hematoxylin. The basal layer was highlighted by cytokeratin 14 (arrows). (b) Nm23H1 and CLDN1 in ESCC with high, moderate, weak and absent staining. Original magnification, × 100 in (a) and × 200 in (b).