Table 8.
Effect of different treatments of A. nitida stem bark crude extract on liver tissue protein, TBARS, H2O2, nitrite and GSH content
| Group | Protein (μg/mg tissue) | TBARS (nM/min/mg) | H2O2 (nM/min/mg tissue) | Nitrite content ( μM/ml) | GSH (μM/g tissue) |
|---|---|---|---|---|---|
| Control | 6.41 ± 0.23a | 1.52 ± 0.08d | 6.38 ± 0.15g | 61.5 ± 1.78d | 47.0 ± 2.84a |
| Vehicle control | 6.14 ± 0.20a | 1.73 ± 0.07c,d | 6.77 ± 0.16g | 64.2 ± 2.83d | 45.65 ± 2.2a |
| CCl4 (1 ml/kg) | 3.98 ± 0.16e | 5.32 ± 0.06a | 18.3 ± 0.26a | 106.3 ± 4.67a | 12.6 ± 1.23d |
| Silymarin + CCl4 | 5.16 ± 0.19b | 2.11 ± 0.08b | 8.37 ± 0.15e | 70.4 ± 0.27c | 46.7 ± 1.77a |
| ANM (200 mg/kg) + CCl4 | 4.42 ± 0.14d | 2.11 ± 0.06b | 12.2 ± 0.21b | 90.2 ± 2.26b | 30.74 ± 1.95c |
| ANM (400 mg/kg) + CCl4 | 5.02 ± 0.14c | 2.02 ± 0.06b,c | 11.1 ± 0.14c | 71.1 ± 1.27c | 41.3 ± 1.68b |
| ANM (200 mg/kg) | 5.90 ± 0.16b,c | 1.81 ± 0.39b | 7.92 ± 0.29d | 61.9 ± 2.75c | 45.4 ± 1.48a,b |
| ANM (400 mg/kg) | 6.48 ± 0.32a | 1.51 ± 0.16d | 7.50 ± 0.29f | 60.0 ± 2.45d | 49.1 ± 1.84a |
Values expressed as means ± SD. Means ± SD with different superscript letter (a–g) within the column indicate significant difference (P < 0.01)