Table 2.

Presence and absence of pathways from obligate symbionts of insects with fully sequenced genomes.

Insect host	Microbe symbiont	Folate biosynthesis	Methionine metabolism	Sulfur metabolism	Genome size (Mbp)
Coptotermes formosanus	Azobacteroides pseudotrichonymphae	Complete	Partial	Partial	1.22
Graphocephala atropunctata	Baumannia cicadellinicola BGSS	Complete	Absent	Complete	0.64
Camponotus chromaiodes	Blochmannia chromaiodes	Complete	Complete	Complete	0.79
Camponotus floridanus	Blochmannia floridanus	Complete	Complete	Complete	0.71
Camponotus pennsylvanicus	Blochmannia pennsylvanicus	Complete	Complete	Complete	0.79
Camponotus vafer	Blochmannia vafer	Complete	Complete	Complete	0.72
Heteropsylla texana	Carsonella ruddii HT	Absent	Absent	Absent	0.16
Heteropsylla cubana	Carsonella ruddii HC	Absent	Absent	Absent	0.17
Ctenarytaina spatulata	Carsonella ruddii CS	Absent	Absent	Absent	0.16
Ctenarytaina eucalypti	Carsonella ruddii CE	Absent	Absent	Absent	0.16
Pachypsylla venusta	Carsonella ruddii PV	Absent	Absent	Absent	0.16
Pachypsylla celtidis	Carsonella ruddii PC	Absent	Absent	Absent	0.16
Bemisia tabaci	Portiera aleyrodidarum	Absent	Absent	Absent	0.35
Acyrthosiphon pisum	Buchnera aphidicola APS	Partial	Absent	Complete	0.66
Acyrthosiphon kondoi	Buchnera aphidicola AK	Partial	Absent	Complete	0.65
Uroleucon ambrosiae	Buchnera aphidicola UA	Partial	Absent	Complete	0.63
Schizaphis graminum	Buchnera aphidicola Sg	Partial	Absent	Complete	0.64
Baizongia pistaciae	Buchnera aphidicola Bp	Partial	Absent	Absent	0.62
Cinara tujafilina	Buchnera aphidicola Ct	Absent	Absent	Absent	0.44
Aspidiotus nerii	Uzinura diaspidicola	Partial	Absent	Absent	0.26
Planococcus citri	Tremblaya princeps	Absent	Absent	Absent	0.14
Planococcus citri	Moranella endobia	Absent	Absent	Absent	0.54
Homalodisca vitripennis	Sulcia muelleri Hc	Absent	Absent	Absent	0.15
Diceroprocta semicincta	Sulcia muelleri DSEM	Absent	Absent	Absent	0.28
Clastoptera arizonana	Sulcia muelleri CARI	Absent	Absent	Absent	0.28
Megacopta punctatissima	Ishikawaella capsulata	Complete	Complete	Partial	0.75
Diceroprocta semicincta	Hodgkinia cicadicola	Absent	Partial	Absent	1.11
Graphocephala atropunctata	Baumannia cicadellinicola BGSS	Complete	Absent	Partial	0.76
Macrosteles quadrilineatus	Nasuia deltocephalinicola	Absent	Partial	Absent	0.11
Pediculus humanus	Riesia pediculicola	Complete	Absent	Absent	0.58
Blattella germanica	Blattabacterium sp. Bge	Complete	Partial	Partial	0.64
Mastotermes darwiniensis	Blattabacterium sp. MADAR	Complete	Absent	Partial	0.59
Cryptocercus punctulatus	Blattabacterium sp. Cpu	Complete	Absent	Absent	0.61
Blaberus giganteus	Blattabacterium sp. BGIGA	Complete	Partial	Absent	0.63
Panesthia angustipennis spadica	Blattabacterium sp. BPAA	Complete	Partial	Absent	0.63
Diaphorina citri	Profftella armatura	Absent	Absent	Partial	0.46
Glossina morsitans morsitans	Wigglesworthia glossinidia	Complete	Absent	Absent	0.72

“Complete” denotes that all of the enzymes for a particular pathway are encoded in the genome. “Partial” denotes that only some enzymes for a particular pathway are encoded in the genome. “Absent” denotes that no orthologs of the enzymes of a particular pathway are present in the genome. Information for gene presence and absence is based on GenBank, KEGG, and BioCyc data.

The selected pathways produce important microbially derived metabolites that may influence insect host DNA methylation patterns.