Table 3.

Body and liver weights

	Group C	Group H	Group HS	Group HDL	Group HDM	Group HDH
Body weights (g)
0W	208.30 ± 11.95	206.10 ± 12.58	205.40 ± 11.69	208.80 ± 7.84	207.90 ± 11.29	207.70 ± 10.31
6W	355.60 ± 27.37	427.40 ± 27.59*	425.20 ± 26.60	422.70 ± 23.86	428.80 ± 17.25	430.40 ± 15.64
10W	398.60 ± 20.92	432.90 ± 31.07*	428.40 ± 22.10	446.30 ± 25.32	453.00 ± 25.28	469.50 ± 25.01†
14W	452.70 ± 15.30	388.90 ± 34.55*	390.10 ± 24.78	423.40 ± 21.43†‡	428.90 ± 26.77†‡	450.60 ± 27.92†‡§
Liver weights (g)
14W	14.79 ± 1.29	21.39 ± 2.52*	15.14 ± 1.69†	16.83 ± 1.29†‡	16.41 ± 1.35†	15.02 ± 2.12†§

C: normal control group, standard rat diet for 14 weeks and treated with 0.9% saline 10 mL/kg every day (n = 10); H: high-fat diet + STZ group, high-fat diet for 14 weeks and treated with 0.9% saline 10 mL/kg every day (n = 15 at 0 week and n = 10 at 6, 10 and 14 weeks); HS: high-fat diet + STZ with simvastatin treated group, high-fat diet for 14 weeks and treated with simvastatin 0.9 mg/10 mL/kg every day (n = 15 at 0 week and n = 10 at 6, 10 and 14 weeks); HDL: high-fat diet + STZ with low dose of DSKT treated group, high-fat diet for 14 weeks and treated with DSKT 3.75 g/10 mL/kg every day (n = 15 at 0 week and n = 10 at 6, 10 and 14 weeks); HDM: high-fat diet + STZ with medial dose of DSKT treated group, high-fat diet for 14 weeks and treated with DSKT 7.5 g/10 mL/kg every day (n = 15 at 0 week and n = 10 at 6, 10 and 14 weeks); HDH: high-fat diet + STZ with high dose of DSKT treated group, high-fat diet for 14 weeks and treated with DSKT 15 g/10 mL/kg every day (n = 15 at 0 week and n = 10 at 6, 10 and 14 weeks). *P < 0.05 vs. Group C, †P < 0.05 vs. Group H, ‡P < 0.05 vs. Group HS, §P < 0.05 vs. Group HDL, ||P < 0.05 vs. Group HDM. Data are expressed as the means ± standard deviation. 0W, 0 week; 6W, 6 weeks; 10W, 10 weeks; 14W, 14 weeks; DSKT, daisaikoto; STZ, streptozotocin.