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. 2016 Aug 3;8:83. doi: 10.1186/s13148-016-0249-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Cellular biomarkers associated with tobacco smoking. Subjects were separated into non-smoker (white diamond), occasional smoker (gray circle), and smoker (black circle) by both a questionnaire and cotinine level in the blood (a). Separately, the content of GPR15+ CD3+ T cells in blood (b) and the degree of methylation at the CpG site cg05575921 within AHRR in granulocytes (c) perfectly indicate the systemic effect of active tobacco smoking on blood cell types