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. 2016 Aug 4;17:99. doi: 10.1186/s12931-016-0409-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Targeted CF6 silencing alleviates hemodynamic changes and right ventricular hypertrophy in PAH rats at 4 weeks after MCT exposure. a Representative hemodynamic data (RVSP) obtained with a Labchart acquisition system. b CF6 shRNA decreased RVSP in the MCT-control group. c CF6 shRNA also reduced the RV/LV + S ratio in the MCT-treated rats. The data represent the mean ± SD. **p < 0.01 and *p < 0.05. RVSP, right ventricle systolic pressure; RV/LV + S ratio, weight ratio of the right ventricle to the left ventricle plus the septum