Fig. 2.

Increased 5-HT1A receptor binding in Deaf1-/- raphe. 5-HT1A receptor autoradiography of representative midbrain (male-M and female-F) and hippocampus (male) sections from Deaf1-/- (KO) and wild-type (WT) mice was done using ¹²⁵I-MPPI. a Representative sections of raphe, including dorsal and median raphe (in boxes), and of hippocampus are shown. b Average signal/region was quantified as described in Methods for dorsal and medial raphe, and hippocampus. Since there was no sex difference in 5-HT1A binding in raphe (WT) and hippocampus (WT and KO), pooled values are shown. Data represent mean ± SEM (n = 4), **p < 0.01; ****p < 0.0001