Table 1.
Biochemical findings of the two patients during the first and the last hospitalization
| Laboratory test | Patient 1 | Patient 2 | Normal values | ||
|---|---|---|---|---|---|
| Initial values age 17 months | Last values age 6 year | Initial values age 5 months | Last values age 8 months | ||
| Serum Ca (mg/dl) | 9.8 | 9.8 | 9.8 | 9.8 | 9–11 |
| Serum PO4 | 2.3 mg/dl | 3.8 mg/dl | 1.3 mg/dl | 1.7 mg/dl | 1 month–2 year: 3.8–6.5 g/dl 3–9 year: 3.2–5.8 mg/dl |
| Serum alkaline phosphatase (U/l) | 666 | 206 | 1200 | 1178 | 150–420 |
| Parathyroid hormone (ng/l) | 47 | 49 | 13 | 83 | 10–65 |
| Vitamin D3 (pg/ml) | 25 | 24 | 27 | 16–65 | |
| Serum triglyceride (mg/dl) | 761 | 187 | 1200 | 254 | 27–125 |
| Serum cholesterol (mg/dl) | 210 | 186 | 400 | 153 | <170 |
| Aspartate aminotransferase (U/l) | 49 | 37 | 140 | 117 | 9–80 |
| Alanine aminotransferase (U/l) | 76 | 32 | 61 | 56 | 13–46 |
| Random blood sugar (mg/dl) | 120 | 135 | 102 | 88 | <126 |
| Serum uric acid (mg/dl) | 1.5 | 1.5 | 1.1 | 2.2–6.6 | |
| Venous pH | 7.32 | 7.42 | 7.25 | 7.30 | 7.35–7.45 |
| HCO3 (mEq/l) | 17 | 22 | 13 | 14 | 18–24 |
| TRP (%) | 59 | 69 | 32 | 33 | >85 |
| Urine calcium excretion (mg/kg/day) | 7.4 | 5.6 | 3.2 | <4 | |
| Glomerular filtration rate (ml/min/1.73 m2) | 83 | 226 | 13 | 98 | 49–165 |
| Urine protein excretion (mg/m2/h) | 64 | 18.8 | 42 | 44 | <4 |
| Urine glucose excretion (g/24 h) | 25.7 | 1.8 | 4.5 | ||