. 2016 Aug 3;11:68. doi: 10.1186/s13000-016-0518-y

Table 3.

Univariate analyses showing HRs for patient OS and DFS conferred age, FIGO stage, histologic subtypes, DEF6, p53, p16 and ER expression (N = 180)

Variables	Total No.	Overall survival (OS)			Disease-free survival (DFS)
Variables	Total No.	HR	95 % CI	P -value	HR	95 % CI	P -value
Age, years				0.990			0.900
≦50	72	1.00^a			1.00^a
>50	108	1.003	0.595–1.693		1.034	0.613–1.745
FIGO stage				0.023*			0.034*
I	86	1.00^a			1.00^a
II	23	1.141	0.518–2.511		1.119	0.509–2.460
III	64	2.282	1.217–4.279		2.166	1.161–4.040
IV	7	5.300	1.173–23.950		4.939	1.100–22.172
Histologic subtypes				0.303			0.284
Serous carcinoma	75	1.00^a			1.00^a
Mucinous carcinoma	36	0.529	0.247–1.135		0.531	0.247–1.138
Endometrioid carcinoma	28	0.786	0.342–1.808		0.882	0.382–2.037
Clear cell carcinoma	41	0.607	0.317–1.162		0.608	0.318–1.163
DEF6				0.013*			0.009*
Scores 0 and 1	62	1.00^a			1.00^a
Scores 2 and 3	118	2.041	1.159–3.594		2.119	1.202–3.737
p16				0.026*			0.031*
Scores 0 and 1	97	1.00^a			1.00^a
Scores 2 and 3	80	1.919	1.082–3.402		1.873	1.057–3.318
p53				0.181			0.205
Scores 1 and 2	81	1.00^a			1.00^a
Scores 0 and 3	98	1.450	0.841–2.499		1.421	0.825–2.448

^aReference category for HR (Hazard Ratio) calculation with variable

CI: Confidence Interval. (*Significant difference)