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. 2016 Jun 23;115(3):346–353. doi: 10.1038/bjc.2016.182

Table 3. Site of recurrence according to mutational status.

  Bone Liver Brain Pleuro-pericardial Lung Adrenal glands
Wild type (n=258) 57 (22%) 39 (15%) 26 (10%) 37 (14%) 89 (35%) 10 (4%)
EGFR (n=27) 0 8 (30%) 16 (59%) 2 (7%) 1 (4%) 0
KRAS G12C (n=91) 54 (59%) 1 (1%) 7 (8%) 9 (10%) 16 (18%) 4 (4%)
KRAS G12V (n=85) 0 4 (5%) 0 80 (94%) 1 (1%) 0
Other KRAS (n=20) 7 (35%) 4 (20%) 2 (10%) 0 (0%) 5 (25%) 2 (10%)
P-value <0.0001 <0.0001 <0.0001 <0.0001 <0.0001 0.13

Abbreviations: EGFR=epidermal growth factor receptor; KRAS=V-Ki-ras2 Kirsten rat sarcoma viral oncogene homologue.

Data are given as n (%).