Skip to main content
. 2016 Jun 23;115(3):346–353. doi: 10.1038/bjc.2016.182

Table 4. Site of recurrence according to variables included in univariate analysis.

  Bone Liver Brain PP Lung Adrenal glands P-value
Gender
Male 78 (66%) 38 (68%) 27 (53%) 86 (67%) 74 (66%) 12 (75%) 0.48
Female 40 (34%) 18 (32%) 24 (47%) 42 (33%) 38 (34%) 4 (25%)  
LNI
Yes 57 (48%) 29 (52%) 26 (51%) 100 (78%) 50 (45%) 11 (69%) <0.0001
No 61 (52%) 27 (48%) 25 (49%) 28 (22%) 62 (55%) 5 (31%)  
Angio-invasion
Yes 30 (25%) 16 (29%) 16 (31%) 97 (76%) 40 (36%) 8 (50%) <0.0001
No 88 (75%) 40 (71%) 35 (69%) 31 (24%) 72 (64%) 8 (50%)  
Neo-adjuvant treatment
Yes 39 (33%) 27 (48%) 15 (30%) 55 (43%) 45 (40%) 5 (31%) 0.22
No 79 (67%) 29 (52%) 36 (70%) 73 (57%) 67 (60%) 11 (69%)  
Adjuvant treatment
Yes 59 (50%) 30 (53%) 26 (51%) 101 (79%) 52 (46%) 11 (69%) <0.0001
No 59 (50%) 26 (47%) 25 (49%) 27 (21%) 60 (54%) 5 (31%)  
LNR ⩾1/3
Yes 5 (9%) 6 (21%) 7 (27%) 75 (75%) 6 (12%) 1 (10) <0.0001
No 52 (91%) 23 (79%) 19 (73%) 25 (25%) 44 (88%) 9 (91%)  
Skip-N2
Yes 2 (11%) 1 (50%) 2 (40%) 0 0 2 (100%) 0.01
No 16 (89%) 1 (50%) 3 (60%) 5 (100%) 5 (100%) 0  
Microscopic N
Yes 6 (11%) 2 (7%) 7 (27%) 6 (6%) 2 (4%) 0 0.01
No 51 (89%) 27 (93%) 19 (73%) 94 (94%) 48 (96%) 11 (100%)  
Resection margins
R0 resection 115 (98%) 55 (98%) 51 (100%) 126 (98%) 109 (97%) 16 (100) 0.84
R1 resection 3 (2%) 1 (2%) 0 2 (2%) 3 (3%) 0 4

Abbreviations: LNI=lymph node involvement; LNR=lymph node ratio; PP=pleural-pericardial. Bold values were used to indicate significant variables.