Figure 1.

Cyclin E1 expression by IHC in USC. Representative immunohistochemical staining for CCNE1 on USC samples scoring 0 (A), 1+ (B) and 2+ (C). A representative negative control (i.e., TMA USC sample stained without the primary antibody, D) and a representative positive control (i.e., cell block from a cell line (ARK2) with known CCNE1 amplification by fluorescent in situ hybridisation (FISH), E) are also shown. (All images at × 200 original magnification.)