Table 1.
Overall sensibility and specificity of the tests
| Test (N = 41) | Panbio® IgM Capture ELISA | Panbio® IgG Capture ELISA | RT-PCR | Combination of the three tests | SD BIOLINE IgM | SD BIOLINE IgG | NS1 antigen | BIOLINE Dengue Duo NS1 + IgM/IgG |
|---|---|---|---|---|---|---|---|---|
| Sensibility % (95CI) | 26.9 (8.0–45.9) | 34.6 (14.4–54.8) | 30.8 (11.1–50.4) | 53.9 (32.8–74.9) | 30.8 (11.1–50.4) | 26.9 (7.9–45.9) | 11.5 (0.0–25.7) | 30.8 (11.1–50.4) |
| Specificity % (95CI) | 86.7 (66.1–100.0) | 60.0 (31.9–88.1) | 93.3 (77.4–100.0) | 80.0 (56.4–100.0) | 73.3 (47.6–99.1) | 66.7 (39.5–93.9) | 100.0 (96.7–100.0) | 73.3 (47.6–99.1) |
| PPV % (95CI) | 77.8 (45.1–100.0) | 60.0 (31.9–88.1) | 88.9 (62.8–100.0) | 82.4 (61.3–100.0) | 66.7 (35.8–97.5) | 58.3 (26.3–90.4) | 100.0 (83.3–100.0) | 66.7 (35.8—97.5) |
| NPV % (95CI) | 40.6 (22.1–59.2) | 34.6 (14.4–54.8) | 43.8 (25.0–62.5) | 50.0 (27.9–72.1) | 37.9 (18.6–57.3) | 34.5 (15.5–53.5) | 39.5 (22.6–56.3) | 37.9 (18.6–57.3) |
95CI = 95% confidence interval; ELISA = enzyme-linked immunosorbent assay; NPV = negative predictive value; PPV = positive predictive value; RT-PCR = real-time polymerase chain reaction.