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. 2016 Aug 4;6:30858. doi: 10.1038/srep30858

Table 3. Non-synonymous mutations detected within the protein coding regions compared to A/Northern-pintail/Washington/40964/2014 (H5N2).

Strain Protein
PB2 PB1 PA HAb NP NA M2 NS1 NS2
A/chicken/BC/FAV8/2014 (H5N2) L386V     L8F, N130T, N416S   R338W, R435M, E368K      
A/chicken/BC/FAV9/2014 (H5N2) M47I, L386V, K721E     L8F, N130T, N416S S3P L35S, R338W, R435M, E368K      
A/turkey/BC/FAV10/2014 (H5N2) L386V L373I   L8F, N130T   E368K      
A/turkey/BC/FAV14/2014 (H5N2) L386V, S534P   G152R L8F, N130T I109Ta E368K   D237G I80V
A/chicken/BC/FAV15/2014 (H5N2) L386V M414V V669I L8F, N130T, N416S T15I R338W, R435M, E368K     R86K
A/chicken/BC/FAV17/2014 (H5N2) L386V     L8F, N130T, N416S   R338W, R435M, E368K     R86K
A/turkey/BC/FAV19/2014 (H5N2) L386V, L435P, S534P     L8F, N130T I109Ta E368K      
A/chicken/BC/FAV20/2014 (H5N2) L386V L298P   L8F, N130T   E368K, I469V      
A/chicken/BC/FAV21/2014 (H5N2) L386V M111T   L8F, N130T, F257L   H274R, E368K   R224K E67K
A/chicken/BC/FAV22/2014 (H5N2) L386V   V700I L8F, N130T   E368K      
A/chicken/BC/FAV23/2014 (H5N2) L386V, S534P     L8F, N130T, D171N I109Ta E368K   V136M  
A/chicken/BC/FAV24/2014 (H5N2) L386V, S534P   G58D, F672L L8F, N130T M105Va, I257T P46L, E368K      
A/chicken/BC/FAV25/2014 (H5N2) M66I, L386V     L8F, N130T, I178V Q327L I305V, D309G, S332Y, E368K      
A/turkey/ON/FAV7/2015 (H5N2) L386V, T530A, I559T, V649I R215Ka   I4T, L8F, N130T, V226M   R253K, V412A, N463D, E368K Q78R I176T  
A/chicken/ON/FAV8/2015 (H5N2) T97A, L386V, V649I   N321K I4T, L8F, N130T, V226M   R253K, V412A, N463D, E368K Q78R I176T  
A/turkey/ON/FAV10/2015 (H5N2) L386V, V649I T25I N321K I4T, L8F, N130T, V226M   E83G, R253K, V412A, N463D, E368K Q78R T127P, I176T  

aPositively selected amino acid changes.

bAmino acid numbering based on the hemagglutinin precursor.