Table 3. Lipoprotein subfractions in CAD participants according to ages.
| Very early | Early | Late | p value | |
|---|---|---|---|---|
| n = 81 | n = 304 | n = 349 | ||
| Lipid parameters | ||||
| TG (mg/dL) | 191.2 ± 105.0 | 176.0 ± 112.4 | 152.5 ± 85.1 | 0.001 |
| TC (mg/dL) | 193.3 ± 42.5 | 192.7 ± 41.8 | 182.5 ± 36.1 | 0.002 |
| HDL-C (mg/dL) | 36.80 ± 7.87 | 41.82 ± 12.45 | 43.01 ± 13.58 | <0.001 |
| LDL-C (mg/dL) | 127.42 ± 42.02 | 128.56 ± 38.05 | 118.94 ± 34.25 | 0.001 |
| HDL subfraction | ||||
| Large HDL (mg/dL) | 10.16 ± 4.31 | 12.47 ± 6.23 | 14.34 ± 7.30 | <0.001 |
| Medium HDL (mg/dL) | 19.01 ± 3.93 | 20.75 ± 6.57 | 21.01 ± 6.44 | 0.035 |
| Small HDL (mg/dL) | 8.10 ± 3.74 | 8.35 ± 3.33 | 8.01 ± 3.29 | 0.435 |
| Large HDL (%) | 26.77 ± 7.52 | 29.10 ± 8.03 | 32.04 ± 7.99 | <0.001 |
| Medium HDL (%) | 51.42 ± 5.58 | 50.04 ± 5.17 | 48.95 ± 4.80 | <0.001 |
| Small HDL (%) | 21.75 ± 7.47 | 20.63 ± 7.54 | 18.95 ± 6.22 | <0.001 |
| LDL subfraction | ||||
| Large LDL (mg/dL) | 27.70 ± 9.52 | 26.87 ± 10.65 | 27.11 ± 8.46 | 0.846 |
| Medium LDL (mg/dL) | 22.24 ± 9.23 | 20.77 ± 8.95 | 19.20 ± 8.98 | 0.039 |
| Small LDL (mg/dL) | 10.80 ± 12.41 | 10.27 ± 10.00 | 7.45 ± 8.33 | 0.003 |
| Large LDL (%) | 14.49 ± 4.46 | 13.86 ± 4.23 | 14.75 ± 3.90 | 0.076 |
| Medium LDL (%) | 11.14 ± 3.12 | 10.50 ± 3.24 | 10.13 ± 3.70 | 0.130 |
| Small LDL (%) | 4.99 ± 4.97 | 5.02 ± 4.51 | 3.79 ± 3.93 | 0.008 |
| Mean LDL particle size (Å) | 265.54 ± 6.13 | 265.42 ± 5.93 | 267.03 ± 5.54 | 0.011 |
Data are expressed as mean ± SD. The bold values indicated statistical significance. TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein.