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. 2016 Jul 15;30(14):1598–1610. doi: 10.1101/gad.283838.116

Figure 2.

Figure 2.

Chromosomal context determines NOR activity status in A. thaliana. (A) The location of NORs (blue) on the top/north arms of chromosomes 2 and 4 (NOR2 and NOR4, respectively). In strain Col-0, NOR2 containing rDNA variants VAR1 and VAR3 is silent (red lettering). NOR4 containing VAR2 and VAR3 rDNA repeats is active (green lettering). In the strain ColSf-NOR4, NOR4 and adjacent sequences from strain Sf-2 (yellow) were introgressed (engineered) into the Col-0 genetic background. The SF-2 NOR4 (yellow) is comprised solely of VAR1 repeats. VAR1 repeats are active (green lettering) in the ColSf-NOR4 context. (B) A model proposing that a NOR inactivation center immediately proximal to NOR2 is responsible for its silencing (Chandrasekhara et al. 2016).